Correlation and hierarchical clustering

Calculates cell to cell correlation matrix based on the PCA feature space and runs hierarchical clustering taking 1 - correlation scores as distance.

correlation_and_hierarchical_clust_scExp(scExp, hc_linkage = "ward.D")

Arguments

scExp	A SingleCellExperiment object, containing 'PCA' in reducedDims.
hc_linkage	A linkage method for hierarchical clustering. See cor. ('ward.D')

Value

Return a SingleCellExperiment object with correlation matrix & hiearchical clustering.

Details

This functions takes as input a SingleCellExperiment object that must have PCA calculated and outputs a SingleCellExperiment object with correlation matrix and hierarchical clustering.

Examples

data("scExp")
scExp_cf = correlation_and_hierarchical_clust_scExp(scExp)